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2.two]decane core and defining the geometry of the exocyclic double bond. The activation energies of development with the vinyl-gold intermediates ended up calculated and unveiled a silyl enol ether by having an unprotected indole moiety as an appropriate precursor for your Toste cyclization. This 6-step synthesis did not involve any nonstrategic r
2.2]decane core and defining the geometry on the exocyclic double bond. The activation energies of development from the vinyl-gold intermediates were being calculated and discovered a silyl enol ether having an unprotected indole moiety as an appropriate precursor for the Toste cyclization. This 6-phase synthesis didn't entail any nonstrategic redo